Detalhe da pesquisa
1.
p53: A tale of complexity and context.
Cell
; 187(7): 1569-1573, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38552605
2.
Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
Cell
; 182(4): 1044-1061.e18, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32795414
3.
Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models.
Cell
; 175(1): 171-185.e25, 2018 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30146162
4.
The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic.
Nature
; 586(7827): 133-138, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728212
5.
A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation.
Mol Cell
; 71(1): 178-190.e8, 2018 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29979965
6.
p53 deficient breast cancer cells reprogram preadipocytes toward tumor-protective immunomodulatory cells.
Proc Natl Acad Sci U S A
; 120(52): e2311460120, 2023 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38127986
7.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.
Mol Syst Biol
; 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38580884
8.
Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins.
Proc Natl Acad Sci U S A
; 119(17): e2119644119, 2022 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35439056
9.
p53 is essential for DNA methylation homeostasis in naïve embryonic stem cells, and its loss promotes clonal heterogeneity.
Genes Dev
; 31(10): 959-972, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607180
10.
ARTS and small-molecule ARTS mimetics upregulate p53 levels by promoting the degradation of XIAP.
Apoptosis
; 2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38684550
11.
TP53 missense mutations in PDAC are associated with enhanced fibrosis and an immunosuppressive microenvironment.
Proc Natl Acad Sci U S A
; 118(23)2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34088837
12.
The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation.
Genes Dev
; 30(7): 786-97, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27013235
13.
Down-regulation of LATS kinases alters p53 to promote cell migration.
Genes Dev
; 29(22): 2325-30, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26588988
14.
Pseudo-mutant P53 is a unique phenotype of DNMT3A-mutated pre-leukemia.
Haematologica
; 107(11): 2548-2561, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199506
15.
A Systematic p53 Mutation Library Links Differential Functional Impact to Cancer Mutation Pattern and Evolutionary Conservation.
Mol Cell
; 71(5): 873, 2018 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30193102
16.
Altered p53 functionality in cancer-associated fibroblasts contributes to their cancer-supporting features.
Proc Natl Acad Sci U S A
; 115(25): 6410-6415, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29866855
17.
Corrigendum: p53 is essential for DNA methylation homeostasis in naïve embryonic stem cells, and its loss promotes clonal heterogeneity.
Genes Dev
; 32(19-20): 1358, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30275045
18.
TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.
Blood
; 131(25): 2789-2802, 2018 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29653964
19.
Nucleosome organization affects the sensitivity of gene expression to promoter mutations.
Mol Cell
; 46(3): 362-8, 2012 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22464732
20.
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis.
Mol Cell
; 45(2): 222-32, 2012 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22284678